With reference to the first article on the topic orbital neoplasias this second part focuses on the main characteristics of mesenchymal, leukemic, lymphoproliferative, osseous as well as secondary neoplasias of the orbit. For each entity the therapeutic approaches are presented. A large number of case report examples underline once more the importance of an efficient diagnostic procedure to ensure sufficient treatment of the lesion itself as well as the relatively common underlying systemic disease.