Complete genome sequence of the NVSL BoHV-1.1 Cooper reference strain

Arch Virol. 2013 May;158(5):1109-13. doi: 10.1007/s00705-012-1574-6. Epub 2012 Dec 20.

Abstract

The only complete genome sequence available for bovine herpesvirus 1 (BoHV-1) is a composite sequence derived from four different BoHV-1.1 strains and one BoHV-1.2 strain. Such a chimeric genome sequence is problematic for molecular genetic studies on this virus. We report here the complete genome sequence for the BoHV-1.1 NVSL reference strain Cooper. Although similar to the published chimeric genome sequence, there are a number of nucleotide substitutions and deletions/insertions across the genome, many of which affect coding sequences.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA, Viral / chemistry*
  • DNA, Viral / genetics*
  • Genome, Viral*
  • Herpesvirus 1, Bovine / genetics*
  • Molecular Sequence Data
  • Sequence Analysis, DNA

Substances

  • DNA, Viral

Associated data

  • GENBANK/JX898220