Silver as antibacterial agent: ion, nanoparticle, and metal

Angew Chem Int Ed Engl. 2013 Feb 4;52(6):1636-53. doi: 10.1002/anie.201205923. Epub 2012 Dec 17.

Abstract

The antibacterial action of silver is utilized in numerous consumer products and medical devices. Metallic silver, silver salts, and also silver nanoparticles are used for this purpose. The state of research on the effect of silver on bacteria, cells, and higher organisms is summarized. It can be concluded that the therapeutic window for silver is narrower than often assumed. However, the risks for humans and the environment are probably limited.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / toxicity
  • Bacteria / drug effects
  • Cell Survival / drug effects
  • Environmental Pollutants / toxicity
  • Fungi / drug effects
  • Humans
  • Ions / chemistry
  • Metal Nanoparticles / chemistry*
  • Metals / chemistry*
  • Silver / chemistry*

Substances

  • Anti-Bacterial Agents
  • Environmental Pollutants
  • Ions
  • Metals
  • Silver