Autonomic function and unmyelinated fibers in chronic inflammatory demyelinating polyradiculoneuropathy

Muscle Nerve. 1990 Jan;13(1):70-6. doi: 10.1002/mus.880130113.


Because autonomic function may be abnormal in some demyelinating peripheral neuropathies, it has been studied with a number of noninvasive and invasive tests in 14 patients with chronic inflammatory demyelinating polyradiculoneuropathy. There were abnormalities of the 30:15 ratio in 3 patients and an abnormal thermoregulatory sweat test in 5 patients. These findings are indicative of mild parasympathetic and sympathetic dysfunction. Minor pathological changes in unmyelinated fibers were demonstrated on morphometric examination of sural nerves of 10 patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Autonomic Nervous System / physiopathology*
  • Child
  • Child, Preschool
  • Demyelinating Diseases / physiopathology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Polyradiculopathy / physiopathology*
  • Sural Nerve / pathology
  • Sural Nerve / physiopathology