Cylindroma of head and neck: review of the literature and report of two rare cases

Abstract

Cylindromas are very rare and benign adnexal tumours of the skin. Very few reports of these benign tumours are reported in the literature. Dermal cylindromas are characterised as a benign neoplasm of the eccrine sweat glands. The most frequent location is the head and neck. Multiple occurrences are often linked to the Brooke-Spiegler syndrome. The Brooke-Spiegler syndrome is inherited as an irregular autosomal dominant trait. A malignant transformation to an adenoid cystic carcinoma is also described in the literature. The leading treatment modality described in the literature is the complete surgical removal of the lesions. Here, a systematic review of the literature is presented with two rare cases of cylindromas.

Keywords: Adenoid cystic carcinoma; Brooke-Spiegler syndrome; Cutaneous cylindroma; Head and neck; Malignant transformation; Recurrence.