A clinical review of small-cell carcinoma of the urinary bladder

Clin Genitourin Cancer. 2013 Jun;11(2):73-7. doi: 10.1016/j.clgc.2012.11.002. Epub 2012 Dec 23.


Small-cell carcinoma of the urinary bladder is a rare and aggressive type of bladder cancer that has a poor prognosis. The incidence has been gradually increasing because of the aging population. Owing to its rarity there are no available treatment guidelines. Several retrospective studies and 1 prospective study have provided some insight into therapy for this disease. A multimodal approach that includes chemotherapy, local radiation therapy, and definitive surgery in resectable cases appears to be an optimal management approach.

Publication types

  • Review

MeSH terms

  • Carcinoma, Small Cell* / epidemiology
  • Carcinoma, Small Cell* / mortality
  • Carcinoma, Small Cell* / therapy
  • Combined Modality Therapy*
  • Humans
  • Male
  • Prognosis
  • Prospective Studies
  • Retrospective Studies
  • Risk Factors
  • Urinary Bladder / pathology
  • Urinary Bladder Neoplasms* / epidemiology
  • Urinary Bladder Neoplasms* / mortality
  • Urinary Bladder Neoplasms* / therapy