Platelet-rich plasma as an effective treatment for proximal hamstring injuries

Orthopedics. 2013 Jan;36(1):e64-70. doi: 10.3928/01477447-20121217-20.


Proximal hamstring injuries can be disabling, and several traditional conservative treatments, including physiotherapy and nonsteroidal anti-inflammatory drugs, have been inconsistent. Corticosteroid injections have demonstrated success but can adversely affect local tissues. Platelet-rich plasma (PRP) has emerged as a safe, effective treatment for several orthopedic pathologies. The authors propose a PRP injection at the muscle origin as a novel treatment for proximal hamstring injuries. A retrospective review yielded 15 patients with 17 proximal hamstring injuries. Twelve injuries failed traditional conservative treatment and were ultimately treated with a PRP injection at the hamstrings muscle origin. Five patients were treated with traditional conservative treatment alone. Analysis included pre- and posttreatment visual analog scale scores, Nirschl Phase Rating Scale scores, and return to sport. No significant difference existed between the groups' pretreatment visual analog scale scores (P=.28) and Nirschl Phase Rating Scale scores (P=.15) and their posttreatment visual analog scale scores (P=.38) and Nirschl Phase Rating Scale scores (P=.22). The PRP group demonstrated a reduction in visual analog scale scores (P<.01) and Nirschl Phase Rating Scale scores (P<.01), but the traditional conservative treatment group did not demonstrate the same reduction (P=.06 and .06, respectively). All athletes returned to their desired activity level with no major complications.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Athletes / statistics & numerical data
  • Female
  • Humans
  • Male
  • Middle Aged
  • Muscle, Skeletal / injuries*
  • Pain Measurement
  • Platelet-Rich Plasma*
  • Recovery of Function
  • Retrospective Studies
  • Soft Tissue Injuries / therapy*
  • Tendinopathy / therapy*
  • Thigh / injuries*
  • Young Adult