Abstract
During 3 years, my research activities in Jack Griffin's laboratory focused on the influence of β-amyloid precursor protein cleaving enzyme 1 (BACE1) on the degeneration/regeneration of sciatic nerve of mice. Here, potential mechanisms of how BACE1 enzymatic activity influences these processes are discussed.
© 2012 Peripheral Nerve Society.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Amyloid Precursor Protein Secretases / metabolism*
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Animals
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Aspartic Acid Endopeptidases / metabolism*
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Mice
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Nerve Regeneration / physiology*
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Peripheral Nerves / metabolism*
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Phagocytosis / physiology*
Substances
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Amyloid Precursor Protein Secretases
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Aspartic Acid Endopeptidases
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Bace1 protein, mouse