Probable Phaeoacremonium parasiticum as a cause of cavitary native lung nodules after single lung transplantation

Transpl Infect Dis. 2013 Feb;15(1):E9-13. doi: 10.1111/tid.12040. Epub 2012 Dec 20.

Abstract

Lung nodules after lung transplantation most often represent infection or post-transplant lymphoproliferative disorder in the allograft. Conversely, native lung nodules in single lung transplant recipients are more likely to be bronchogenic carcinoma. We present a patient who developed native lung cavitary nodules. Although malignancy was anticipated, evaluation revealed probable Phaeoacremonium parasiticum infection. Phaeoacremonium parasiticum is a dematiaceous fungus first described as a cause of soft tissue infection in a renal transplant patient. Lung nodules have not been previously described and this is the first case, to our knowledge, of P. parasiticum identified after lung transplantation.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Humans
  • Immunocompromised Host
  • Lung Diseases, Fungal / diagnosis
  • Lung Diseases, Fungal / microbiology*
  • Lung Transplantation*
  • Male
  • Multiple Pulmonary Nodules
  • Mycoses / diagnosis
  • Mycoses / microbiology*
  • Phialophora / isolation & purification*
  • Tomography Scanners, X-Ray Computed