Plant mechanosensing and Ca2+ transport

Trends Plant Sci. 2013 Apr;18(4):227-33. doi: 10.1016/j.tplants.2012.12.002. Epub 2013 Jan 3.


Mechanical stimuli generate Ca(2+) signals and influence growth and development in plants. Recently, candidates for Ca(2+)-permeable mechanosensitive (MS) channels have been identified. These channels are thought to be responsible for sensing osmotic shock, touch, and gravity. One candidate is the MscS-like (MSL) protein family, a homolog of the typical bacterial MS channels. Some of the MSL proteins are localized to plastids to maintain their shape and size. Another candidate is the mid1-complementing activity (MCA) protein family, which is structurally unique to the plant kingdom. MCA proteins are localized in the plasma membrane and are suggested to be involved in mechanosensing and to be functionally related to reactive oxygen species (ROS) signaling. Here, we review their structural features and role in planta.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Calcium / metabolism*
  • Calcium Channels / metabolism
  • Conserved Sequence
  • Mechanotransduction, Cellular / physiology*
  • Membrane Proteins / metabolism
  • Molecular Sequence Data
  • Osmotic Pressure
  • Phylogeny
  • Plant Development
  • Plant Proteins / metabolism
  • Plants
  • Protein Transport
  • Reactive Oxygen Species / metabolism*
  • Sequence Alignment
  • Stress, Physiological


  • Calcium Channels
  • Membrane Proteins
  • Plant Proteins
  • Reactive Oxygen Species
  • Calcium