A fully digital photoplethysmographic (PPG) sensor and actuator has been developed. The sensing circuit uses one Light Emitting Diode (LED) for emitting light into human tissue and one LED for detecting the reflectance light from human tissue. A Field Programmable Gate Array (FPGA) is used to control the LEDs and determine the PPG and Blood Oxygen Saturation (S(p)O(2)). The configurations with two LEDs and four LEDs are developed for measuring PPG signal and Blood Oxygen Saturation (S(p)O(2)). N-LEDs configuration is proposed for multichannel S(p)O(2) measurements. The approach resulted in better spectral sensitivity, increased and adjustable resolution, reduced noise, small size, low cost and low power consumption.