Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) remains one of the major multiple antibiotic-resistant bacterial pathogens causing serious community-associated and health care-associated infections. It is now pervasive in the obstetric population associated with skin and soft tissue infections, mastitis, episiotomy, and cesarean wound infections and urinary tract infections. This review addresses the epidemiology, definitions, microbiology, and pathogenesis as well as common clinical presentations. A discussion of the 2011 Infectious Diseases Society of America MRSA treatment guidelines details available antibiotics, invasive and noninvasive MRSA management, and specific factors related to obstetrics. Finally, prevention strategies including decolonization are discussed.
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
MeSH terms
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Anti-Bacterial Agents / therapeutic use*
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Community-Acquired Infections / diagnosis
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Community-Acquired Infections / drug therapy
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Female
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Humans
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Methicillin-Resistant Staphylococcus aureus*
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Pregnancy
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Pregnancy Complications, Infectious / diagnosis
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Pregnancy Complications, Infectious / drug therapy*
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Pregnancy Complications, Infectious / epidemiology
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Pregnancy Complications, Infectious / microbiology
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Pregnancy Complications, Infectious / prevention & control
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Risk Factors
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Soft Tissue Infections / diagnosis
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Soft Tissue Infections / drug therapy*
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Soft Tissue Infections / epidemiology
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Soft Tissue Infections / microbiology
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Soft Tissue Infections / prevention & control
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Staphylococcal Skin Infections / diagnosis
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Staphylococcal Skin Infections / drug therapy*
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Staphylococcal Skin Infections / epidemiology
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Staphylococcal Skin Infections / microbiology
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Staphylococcal Skin Infections / prevention & control