Chemical constituents of Spatholobus suberectus

Chin J Nat Med. 2012 Jan;10(1):32-5. doi: 10.1016/S1875-5364(12)60007-7.

Abstract

Aim: To investigate chemical constituents of Spatholobus suberectus Dunn.

Methods: Isolation and purification were carried out by column chromatographic methods. Compounds were characterized based on their physical characteristics and spectra data.

Results: Seventeen compounds were isolated from ethanol extract of S. suberectus. The structures were elucidated as prestegane B (1), (2R, 3R)-buteaspermanol (2), (+)-medioresinol (3), (2R, 3R)-3,7-dihydroxyflavanone (4), benzeneethanol (5), 4, 7, 2'-trihydroxy-4'-methoxyisoflavanol (6), naringenin (7), blumenol A (8), protocatechuic acid ethyl ester (9), liquiritigenin (10), 7, 4'-dihydroxy-8-methoxy-isoflavone (11), 3, 5, 7, 3', 5'-pentahydroxyflavanone (12), protocatechuic acid (13), glycyroside (14), 8-methylretusin-7-O-β-D-glucopyranoside (15), 3, 3', 4', 5, 6, 7, 8-heptahydroxyflavan (16), and dulcisflavan (17).

Conclusion: All compounds are firstly isolated from the title plant and compounds 1, 3 were isolated from the Spatholobus genus for the first time.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 4-Butyrolactone / analogs & derivatives
  • 4-Butyrolactone / chemistry
  • 4-Butyrolactone / isolation & purification
  • Fabaceae / chemistry*
  • Lignans / chemistry
  • Lignans / isolation & purification
  • Molecular Structure
  • Plant Extracts / chemistry*

Substances

  • Lignans
  • Plant Extracts
  • medioresinol
  • prestegane B
  • 4-Butyrolactone