Functional MHC class II is upregulated in neurofibromin-deficient Schwann cells

J Invest Dermatol. 2013 May;133(5):1372-5. doi: 10.1038/jid.2012.488. Epub 2013 Jan 10.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Cells, Cultured
  • Genes, MHC Class II / genetics
  • Genes, MHC Class II / physiology*
  • HLA-DP Antigens / metabolism
  • HLA-DQ Antigens / metabolism
  • HLA-DR Antigens / metabolism
  • Histocompatibility Antigens Class II / genetics
  • Histocompatibility Antigens Class II / metabolism*
  • Humans
  • Neurofibroma
  • Neurofibromatosis 1 / metabolism
  • Neurofibromatosis 1 / pathology
  • Neurofibromin 1 / deficiency*
  • Neurofibromin 1 / genetics
  • Neurofibromin 1 / metabolism
  • Peripheral Nerves / metabolism
  • Peripheral Nerves / pathology
  • Phenotype
  • Schwann Cells / metabolism*
  • Schwann Cells / pathology
  • Up-Regulation / genetics
  • Up-Regulation / physiology*

Substances

  • HLA-DP Antigens
  • HLA-DQ Antigens
  • HLA-DR Antigens
  • Histocompatibility Antigens Class II
  • Neurofibromin 1