Plasma cell granuloma of the brain

Surg Neurol. 1990 May;33(5):347-52. doi: 10.1016/0090-3019(90)90204-3.


We describe a 29-year-old woman with a plasma cell granuloma arising in the right superior temporal gyrus. The mass appeared on computed tomography as a well-circumscribed area of increased density that markedly enhanced with administration of contrast. Microscopic examination showed a mixed cell population with a predominance of plasma cells, including plasma cells showing cytologic atypia, as well as necrosis with polymorphonuclear leukocytes, and the tumor was characterized immunohistochemically by polyclonal plasma cell proliferation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / pathology
  • Brain / ultrastructure
  • Brain Diseases / diagnosis
  • Brain Diseases / pathology*
  • Dura Mater / pathology
  • Dura Mater / ultrastructure
  • Female
  • Granuloma / pathology*
  • Granuloma, Plasma Cell / diagnosis
  • Granuloma, Plasma Cell / pathology*
  • Humans
  • Immunohistochemistry
  • Microscopy, Electron
  • Necrosis / pathology
  • Neoplasm Invasiveness
  • Neutrophils / pathology