Endophthalmitis caused by Acinetobacter baumanni: a case series

Eye (Lond). 2013 Mar;27(3):450-2. doi: 10.1038/eye.2012.277. Epub 2013 Jan 11.

Abstract

Purpose: To profile the etiology, clinical outcomes and drug sensitivity patterns in endophthalmitis caused by Acinetobacter baumanni.

Methods: Retrospective analysis of all the cases of Acinetobacter baumanni endophthalmitis presenting to tertiary referral care ophthalmic hospital in Eastern India from January 2009 to December 2011 were done.

Results: A total of four cases were included in the study. Out of the four cases one was post traumatic and the rest were post cataract surgery. All the cases underwent vitreoretinal surgical intervention followed by intravitreal antibiotics. A. Baumanni was isolated from vitreous in all the cases. Among all the drugs tested bacteria were found sensitive to ciprofloxacin (100 %) whereas all tested resistant to ceftazidime. Out of the four cases one had to be eviscerated, another developed retinal detachment post vitrectomy, one was phthisical at final followup, and only one patient achieved a vision of 20/200 with clear media and attached retina at final visit.

Conclusion: A. Baumanni is a very rare cause of endophthalmitis with poor visual and anatomical outcomes. Ciprofloxacin should be considered as first the line intravitreal antibiotic.

Publication types

  • Case Reports

MeSH terms

  • Acinetobacter Infections / diagnosis
  • Acinetobacter Infections / drug therapy
  • Acinetobacter Infections / microbiology*
  • Acinetobacter baumannii / isolation & purification*
  • Aged
  • Anti-Infective Agents / therapeutic use
  • Cataract Extraction
  • Child
  • Ciprofloxacin / therapeutic use
  • Endophthalmitis / diagnosis
  • Endophthalmitis / drug therapy
  • Endophthalmitis / microbiology*
  • Eye Infections, Bacterial / diagnosis
  • Eye Infections, Bacterial / drug therapy
  • Eye Infections, Bacterial / microbiology*
  • Eye Injuries, Penetrating / microbiology
  • Female
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Postoperative Complications
  • Retrospective Studies
  • Visual Acuity
  • Vitreous Body / microbiology

Substances

  • Anti-Infective Agents
  • Ciprofloxacin