Structures of fluoro, amino, and thiol inhibitors bound to the [Fe4S4] protein IspH

Angew Chem Int Ed Engl. 2013 Feb 11;52(7):2118-21. doi: 10.1002/anie.201208469. Epub 2013 Jan 10.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amines / chemistry*
  • Binding Sites
  • Catalytic Domain
  • Crystallography, X-Ray
  • Enzyme Inhibitors / chemistry*
  • Escherichia coli / enzymology
  • Escherichia coli Proteins / antagonists & inhibitors*
  • Escherichia coli Proteins / metabolism
  • Fluorine / chemistry*
  • Oxidoreductases / antagonists & inhibitors*
  • Oxidoreductases / metabolism
  • Sulfhydryl Compounds / chemistry*

Substances

  • Amines
  • Enzyme Inhibitors
  • Escherichia coli Proteins
  • Sulfhydryl Compounds
  • Fluorine
  • Oxidoreductases
  • ispH protein, E coli