Testosterone Responses to Intensive Interval Versus Steady-State Endurance Exercise

J Endocrinol Invest. 2012 Dec;35(11):947-50. doi: 10.1007/BF03346740.

Abstract

Free testosterone (FT) hormonal responses were compared between high-intensity interval exercise (IE) and steadystate endurance exercise (SSE) in endurance trained males (no.=15). IE session was repeated periods of 90-sec treadmill running at 100-110% maximal oxygen uptake (VO2max) and 90-sec active recovery at 40% VO2max for 42-47 min. The SSE session consisted of a continuous 45-min run at 60-65% VO2max. Total work output was equal for each exercise session. A 45-min supine rest control session (CON) was also performed. All three sessions were on separate days. Pre-session (PRE), immediate post-session (POST), and 12-h post-session (12POST) blood samples were collected and used to determine FT, SHBG, LH, 3- α-androstanediol glucuronide (3-α Diol G) and cortisol. Analysis of variance compared IE and SSE biomarker responses to the reference CON session. IE and SSE each caused an increase (p<0.01) in FT, but IE more so than SSE (p<0.05). The 5α-reductase marker 3-α Diol G response at 12POST IE was elevated while FT was reduced (p<0.05); no such change occurred following SSE. These findings suggest IE might produce a more pronounced turnover of FT by androgen sensitive tissue than the SSE form of exercise.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Androstane-3,17-diol / analogs & derivatives
  • Androstane-3,17-diol / blood
  • Exercise / physiology*
  • Humans
  • Hydrocortisone / blood
  • Luteinizing Hormone / blood
  • Male
  • Physical Endurance / physiology*
  • Sex Hormone-Binding Globulin / metabolism
  • Testosterone / blood*

Substances

  • Sex Hormone-Binding Globulin
  • Androstane-3,17-diol
  • androstane-3,17-diol glucuronide
  • Testosterone
  • Luteinizing Hormone
  • Hydrocortisone