Damned if you do, damned if you don't: the conundrum of adipose tissue vascularization

Mustafa Yilmaz; Gökhan S Hotamisligil

doi:10.1016/j.cmet.2012.12.014

Damned if you do, damned if you don't: the conundrum of adipose tissue vascularization

Cell Metab. 2013 Jan 8;17(1):7-9. doi: 10.1016/j.cmet.2012.12.014.

Authors

Mustafa Yilmaz¹, Gökhan S Hotamisligil

Affiliation

¹ Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA.

PMID: 23312279
DOI: 10.1016/j.cmet.2012.12.014

Abstract

The plasticity of adipose tissue requires highly regulated changes in accompanying blood vessels. In obesity, adipose tissue angiogenesis plays a complex role to support tissue growth and promote metabolic disease. Emerging research (Sung et al., 2013) indicates that exploiting the mediators of adipose tissue angiogenesis may offer the possibility for therapeutic interventions.

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