Abstract
We report on a patient with Lyme disease who presented with chronic bilateral otitis media and cranial neuropathy with rapid progressive hearing loss. After ceftriaxone and high-dose intravenous immunoglobulins, the disease was controlled only with methylprednisolone and cyclophosphamide. The relationship between Lyme disease and granulomatous vasculitis is discussed. Lyme disease should be kept in mind in the differential diagnosis of various otolaryngological and neurological presentations.
Copyright © 2013 Elsevier Inc. All rights reserved.
MeSH terms
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Anti-Inflammatory Agents / administration & dosage
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Chronic Disease
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Cranial Nerve Diseases / complications
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Cyclophosphamide / administration & dosage
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Disease Progression
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Fatal Outcome
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Granuloma / complications*
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Hearing Loss, Bilateral / diagnosis
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Hearing Loss, Bilateral / etiology*
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Humans
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Lyme Disease / complications*
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Male
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Methylprednisolone / administration & dosage
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Middle Aged
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Myocardial Infarction / complications
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Otitis Media / complications*
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Otoscopy
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Tympanic Membrane Perforation / complications
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Vasculitis / complications
Substances
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Anti-Inflammatory Agents
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Cyclophosphamide
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Methylprednisolone