In situ amplified electronic signal for determination of low-abundance proteins coupling with nanocatalyst-based redox cycling

Juan Tang; Jun Zhou; Qunfang Li; Dianping Tang; Guonan Chen; Huanghao Yang

doi:10.1039/c2cc38493k

In situ amplified electronic signal for determination of low-abundance proteins coupling with nanocatalyst-based redox cycling

Chem Commun (Camb). 2013 Feb 21;49(15):1530-2. doi: 10.1039/c2cc38493k.

Authors

Juan Tang¹, Jun Zhou, Qunfang Li, Dianping Tang, Guonan Chen, Huanghao Yang

Affiliation

¹ Ministry of Education & Fujian Provincial Key Laboratory of Analysis and Detection of Food Safety, Department of Chemistry, Fuzhou University, Fuzhou 350108, PR China.

PMID: 23322322
DOI: 10.1039/c2cc38493k

Abstract

Platinum-cerium oxide hybrid nanocatalysts (CeO(2)-Pt) were for the first time designed as bionanolabels for highly efficient electrochemical immunosensing of low-abundance proteins coupling nanocatalyst-based redox cycling with in situ signal amplification strategy.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Carcinoembryonic Antigen / analysis
Catalysis
Cerium / chemistry
Electrochemical Techniques*
Immunoassay*
Metal Nanoparticles / chemistry*
Nitrophenols / chemistry
Oxidation-Reduction
Oxides / chemistry
Platinum / chemistry
Polymers / chemistry
Proteins / analysis*

Substances

Carcinoembryonic Antigen
Nitrophenols
Oxides
Polymers
Proteins
platinum oxide
Cerium
Platinum
ceric oxide
4-nitrophenol