Unusual myoid, perivascular, and postradiation lesions, with emphasis on atypical vascular lesion, postradiation cutaneous angiosarcoma, myoepithelial tumors, myopericytoma, and perivascular epithelioid cell tumor

Semin Diagn Pathol. 2013 Feb;30(1):73-84. doi: 10.1053/j.semdp.2012.01.006.

Abstract

In recent years, a number of new soft tissue tumor entities have been described that occur in the skin only, or that also occur in other sites but form clinically and pathologically distinct subsets when arising in the skin and subcutaneous tissue. These include a variety of mesenchymal lineages and have variable malignant potential, although superficial malignant soft tissue tumors generally have a more favorable outcome than their more deeply located counterparts. This article reviews the clinical and pathologic features and differential diagnoses of atypical vascular lesion, postradiation cutaneous angiosarcoma, myoepithelioma, myopericytoma, and perivascular epithelioid cell tumor.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / metabolism
  • Hemangiosarcoma / etiology
  • Hemangiosarcoma / metabolism
  • Hemangiosarcoma / pathology*
  • Humans
  • Myoepithelioma / metabolism
  • Myoepithelioma / pathology*
  • Neoplasms, Radiation-Induced / etiology
  • Neoplasms, Radiation-Induced / metabolism
  • Neoplasms, Radiation-Induced / pathology*
  • Pericytes / metabolism
  • Pericytes / pathology
  • Perivascular Epithelioid Cell Neoplasms / metabolism
  • Perivascular Epithelioid Cell Neoplasms / pathology*
  • Radiotherapy / adverse effects
  • Skin Neoplasms / metabolism
  • Skin Neoplasms / pathology*
  • Vascular Neoplasms / etiology
  • Vascular Neoplasms / metabolism
  • Vascular Neoplasms / pathology*

Substances

  • Biomarkers, Tumor