Psychostimulant and nootropic effect of major and trace element composition

O G Afanasieva; N I Suslov; I V Shilova

doi:10.1007/s10517-012-1918-y

Psychostimulant and nootropic effect of major and trace element composition

Bull Exp Biol Med. 2012 Dec;154(2):224-7. doi: 10.1007/s10517-012-1918-y.

Authors

O G Afanasieva¹, N I Suslov, I V Shilova

Affiliation

¹ Laboratory of Phytopharmacology, Institute of Pharmacology, Siberian Division of Russian Academy of Medical Sciences, Tomsk, Russia. olgaafanasjeva@mail.ru

PMID: 23330131
DOI: 10.1007/s10517-012-1918-y

Abstract

We studied the effect of a composition of major and trace elements including calcium chloride, sodium chloride, iron (II) sulfate, zinc sulfate, chromium (III) chloride, and potassium bromide on orientation and exploratory behavior and conditioned response of animals in the open field test and conditioned drinking response in a multiple T-maze with three junctions. The test compound exhibited psychostimulant and nootropic activities.

MeSH terms

Animals
Bromides / metabolism
Calcium Chloride / metabolism
Central Nervous System Stimulants / metabolism*
Chlorides / metabolism
Chromium Compounds / metabolism
Male
Mice
Potassium Compounds / metabolism
Sodium Chloride / metabolism
Sulfates / metabolism
Trace Elements / metabolism*

Substances

Bromides
Central Nervous System Stimulants
Chlorides
Chromium Compounds
Potassium Compounds
Sulfates
Trace Elements
Sodium Chloride
chromous chloride
Calcium Chloride
potassium bromide