Neonatal paracorporeal lung assist device for respiratory failure

Ann Thorac Surg. 2013 Feb;95(2):692-4. doi: 10.1016/j.athoracsur.2012.05.128.


Neonates who experience respiratory failure despite maximal ventilatory support have only extracorporeal membrane oxygenation as a rescue therapy, but it has very poor outcomes as a bridge to transplantation. A pumpless lung-assist device has been used in adults as a bridge to lung transplantation. An alternative membrane oxygenator, the Quadrox iD, is a suitable size for neonatal blood flow. Here we report the use of the Quadrox iD membrane oxygenator with central cannulation as a paracorporeal respiratory support therapy for a neonate with alveolar capillary dysplasia awaiting lung transplantation.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Infant, Newborn
  • Male
  • Oxygenators, Membrane*
  • Persistent Fetal Circulation Syndrome / complications*
  • Pulmonary Alveoli / abnormalities
  • Respiratory Insufficiency / etiology*
  • Respiratory Insufficiency / therapy*

Supplementary concepts

  • Alveolar capillary dysplasia