Management of juvenile myasthenia gravis

Pediatr Neurol. 2013 Feb;48(2):95-104. doi: 10.1016/j.pediatrneurol.2012.07.008.


Juvenile myasthenia gravis is an uncommon autoimmune disorder. Its management is not standardized. Juvenile myasthenia gravis is pathophysiologically similar to myasthenia gravis in adults. However, a number of significant particularities related to race, age at onset, severity, and antibody status complicate the management. We summarize the unique clinical features of juvenile myasthenia gravis and review the therapeutic options.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Age of Onset
  • Child
  • Cholinesterase Inhibitors / therapeutic use
  • Humans
  • Immunosuppression Therapy
  • Myasthenia Gravis / drug therapy
  • Myasthenia Gravis / surgery
  • Myasthenia Gravis / therapy*
  • Thymectomy


  • Cholinesterase Inhibitors