Trendspotting in the Protein Data Bank

FEBS Lett. 2013 Apr 17;587(8):1036-45. doi: 10.1016/j.febslet.2012.12.029. Epub 2013 Jan 18.


The Protein Data Bank (PDB) was established in 1971 as a repository for the three dimensional structures of biological macromolecules. Since then, more than 85000 biological macromolecule structures have been determined and made available in the PDB archive. Through analysis of the corpus of data, it is possible to identify trends that can be used to inform us abou the future of structural biology and to plan the best ways to improve the management of the ever-growing amount of PDB data.

Publication types

  • Review

MeSH terms

  • Crystallography, X-Ray
  • Databases, Protein / statistics & numerical data*
  • Databases, Protein / trends
  • Information Storage and Retrieval / statistics & numerical data*
  • Information Storage and Retrieval / trends
  • Models, Molecular
  • Nucleic Acid Conformation
  • Nucleic Acids / chemistry
  • Nucleic Acids / metabolism
  • Protein Binding
  • Protein Conformation*
  • Proteins / chemistry*
  • Proteins / metabolism


  • Nucleic Acids
  • Proteins