Expression of NMDA receptor-dependent LTP in the hippocampus: bridging the divide

Mol Brain. 2013 Jan 22;6:5. doi: 10.1186/1756-6606-6-5.

Abstract

A consensus has famously yet to emerge on the locus and mechanisms underlying the expression of the canonical NMDA receptor-dependent form of LTP. An objective assessment of the evidence leads us to conclude that both presynaptic and postsynaptic expression mechanisms contribute to this type of synaptic plasticity.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Hippocampus / physiology*
  • Humans
  • Long-Term Potentiation / physiology*
  • Models, Biological
  • Receptors, N-Methyl-D-Aspartate / metabolism*
  • Synapses / physiology

Substances

  • Receptors, N-Methyl-D-Aspartate