Hospital-based surveillance for rotavirus gastroenteritis using molecular testing and immunoassay during the 2011 season in Botswana

Pediatr Infect Dis J. 2013 May;32(5):570-2. doi: 10.1097/INF.0b013e3182847295.

Abstract

We describe rotavirus testing and clinical characteristics for children admitted with acute gastroenteritis during Botswana's 2011 rotavirus season. The rotavirus season extended from June to October with rotavirus-specific case fatality being 2.8%. Using molecular testing as reference, the immunochromatographic test had a sensitivity of 76.5% and specificity of 68.0%. Rotavirus vaccine may significantly reduce childhood morbidity and mortality in Botswana.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Botswana / epidemiology
  • Child
  • Child, Preschool
  • Cohort Studies
  • Feces / virology
  • Gastroenteritis / epidemiology*
  • Gastroenteritis / virology
  • Hospitals
  • Humans
  • Immunoassay
  • Infant
  • Molecular Diagnostic Techniques
  • Polymerase Chain Reaction
  • Prospective Studies
  • Public Health Surveillance
  • Rotavirus
  • Rotavirus Infections / epidemiology*
  • Rotavirus Infections / virology