Utility of antimüllerian Hormone Level Obtained for Infertility Assessment for Alerting to Ovarian Tumor

Obstet Gynecol. 2013 Feb;121(2 Pt 2 Suppl 1):454-7. doi: 10.1097/aog.0b013e31827d8ff3.

Abstract

Background: Antimüllerian hormone is a marker of ovarian reserve and is now routinely measured in women seeking infertility treatment.

Case: A 42-year-old woman, gravida 1, abortus 1, presented with secondary infertility. Obtained originally for assessment of ovarian reserve, an antimüllerian hormone of more than 160 ng/mL raised suspicion for a granulosa cell tumor. A laparoscopic right salpingo-oophorectomy, pelvic washings, dilation and curettage, and peritoneal and omental biopsies were performed. A well-differentiated granulosa cell tumor confined to the right ovary was consistent with stage 1A disease.

Conclusion: As the use of antimüllerian hormone becomes more common for ovarian reserve testing, providers need to maintain an awareness for neoplastic disease with abnormal values.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Mullerian Hormone / blood*
  • Biomarkers, Tumor / blood*
  • Female
  • Granulosa Cell Tumor / blood
  • Granulosa Cell Tumor / diagnosis*
  • Granulosa Cell Tumor / surgery
  • Humans
  • Infertility, Female / blood
  • Ovarian Neoplasms / blood
  • Ovarian Neoplasms / diagnosis*
  • Ovarian Neoplasms / surgery
  • Ovariectomy
  • Salpingectomy

Substances

  • Biomarkers, Tumor
  • Anti-Mullerian Hormone

Supplementary concepts

  • Granulosa cell tumor of the ovary