Information processing varies between insomnia types: measures of N1 and P2 during the night

Behav Sleep Med. 2013;11(1):56-72. doi: 10.1080/15402002.2012.660896.


This study compared cortical arousal mechanisms during the night using event-related potentials (N1 and P2), and compared sleep misperception in 30 adults with psychophysiological insomnia (Psy-I), 28 adults with paradoxical insomnia (Para-I), and 30 good sleepers (GS). Participants (age range = 25-55 years) spent 4 consecutive nights in the laboratory, and Night-4 data were used for analysis. N1 amplitude was generally larger in both insomnia groups compared to GS, and P2 amplitude was larger in Para-I than in the 2 other groups, especially in REM sleep. Results suggest that, although hyperarousal appears to persist during sleep in adults with insomnia, inhibition deficits are more likely to be present in Para-I compared to Psy-I.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Arousal / physiology*
  • Attitude to Health
  • Brain Waves / physiology*
  • Case-Control Studies
  • Cerebral Cortex / physiopathology
  • Evoked Potentials, Auditory / physiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Polysomnography
  • Severity of Illness Index
  • Sleep Initiation and Maintenance Disorders / classification*
  • Sleep Initiation and Maintenance Disorders / diagnosis
  • Sleep Initiation and Maintenance Disorders / physiopathology*
  • Sleep Initiation and Maintenance Disorders / psychology