Nipah virus infection outbreak with nosocomial and corpse-to-human transmission, Bangladesh

Emerg Infect Dis. 2013 Feb;19(2):210-7. doi: 10.3201/eid1902.120971.


Active Nipah virus encephalitis surveillance identified an encephalitis cluster and sporadic cases in Faridpur, Bangladesh, in January 2010. We identified 16 case-patients; 14 of these patients died. For 1 case-patient, the only known exposure was hugging a deceased patient with a probable case, while another case-patient's exposure involved preparing the same corpse for burial by removing oral secretions and anogenital excreta with a cloth and bare hands. Among 7 persons with confirmed sporadic cases, 6 died, including a physician who had physically examined encephalitis patients without gloves or a mask. Nipah virus-infected patients were more likely than community-based controls to report drinking raw date palm sap and to have had physical contact with an encephalitis patient (29% vs. 4%, matched odds ratio undefined). Efforts to prevent transmission should focus on reducing caregivers' exposure to infected patients' bodily secretions during care and traditional burial practices.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Arecaceae
  • Bangladesh / epidemiology
  • Beverages
  • Burial
  • Cadaver
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Cross Infection / mortality
  • Cross Infection / transmission*
  • Cross Infection / virology
  • Disease Outbreaks*
  • Encephalitis, Viral / mortality
  • Encephalitis, Viral / transmission*
  • Encephalitis, Viral / virology
  • Epidemiological Monitoring
  • Female
  • Henipavirus Infections / mortality
  • Henipavirus Infections / transmission*
  • Henipavirus Infections / virology
  • Humans
  • Infectious Disease Transmission, Patient-to-Professional
  • Male
  • Middle Aged
  • Nipah Virus*
  • Physicians
  • Risk Factors
  • Young Adult