Innate Lymphoid Cells--A Proposal for Uniform Nomenclature

Nat Rev Immunol. 2013 Feb;13(2):145-9. doi: 10.1038/nri3365.

Abstract

Innate lymphoid cells (ILCs) are a family of developmentally related cells that are involved in immunity and in tissue development and remodelling. Recent research has identified several distinct members of this family. Confusingly, many different names have been used to characterize these newly identified ILC subsets. Here, we propose that ILCs should be categorized into three groups based on the cytokines that they can produce and the transcription factors that regulate their development and function.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biomarkers / metabolism
  • Guidelines as Topic
  • Humans
  • Immunity, Innate*
  • Immunophenotyping
  • Lymphocytes / classification
  • Lymphocytes / immunology*
  • Lymphocytes / metabolism

Substances

  • Biomarkers