Infiltrating Lobular Breast Cancer: Truly a Separate Entity! Consequences for Radiation Therapy

Radiother Oncol. 2013 Jan;106(1):1-4. doi: 10.1016/j.radonc.2012.12.010. Epub 2013 Jan 22.


Infiltrating lobular cancer is known for its diffuse growth pattern and difficult radiological visualization. Based on this review, infiltrating lobular cancer patients do not have a higher local recurrence risk after breast conserving therapy. Lobular histology should also be considered as a separate prognostic factor in favour of referral for radiotherapy after mastectomy.

MeSH terms

  • Breast Neoplasms / radiotherapy*
  • Carcinoma, Lobular / radiotherapy*
  • Female
  • Humans
  • Mastectomy
  • Mastectomy, Segmental