Frequency-domain optical coherence tomography assessment of very late vascular response after carotid stent implantation

J Vasc Surg. 2013 Jul;58(1):201-4. doi: 10.1016/j.jvs.2012.11.038. Epub 2013 Jan 26.


Intravascular optical coherence tomography is a high-resolution invasive imaging modality that allows the evaluation of vascular responses after stent implantation in a micron-scale level. We describe for the first time two patients with very late vascular response after carotid artery stenting that exhibit two different patterns of low-signal intensity (LSI), "ill-appearing" neointima: the first patient shows layered LSI neointima leading to stent restenosis, coupled with the presence of intraluminal thrombus, whereas the second patient demonstrates another pattern of non-restenotic LSI stent strut coverage, suggestive of lipid laden neointima (ie, "neoatherosclerosis"), recently associated with stent failure in coronary arteries.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Angioplasty / adverse effects
  • Angioplasty / instrumentation*
  • Carotid Artery, Internal / diagnostic imaging
  • Carotid Artery, Internal / pathology*
  • Carotid Stenosis / diagnosis
  • Carotid Stenosis / therapy*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neointima
  • Plaque, Atherosclerotic
  • Radiography
  • Recurrence
  • Stents*
  • Time Factors
  • Tomography, Optical Coherence*
  • Treatment Outcome