a website and repository for accessing, analysing and manipulating metabolic networks

Bioinformatics. 2013 Mar 15;29(6):815-6. doi: 10.1093/bioinformatics/btt036. Epub 2013 Jan 28.

Abstract is a website for accessing, analysing and manipulating genome-scale metabolic networks (GSMs) as well as biochemical pathways. It consistently integrates data from various public resources and makes the data accessible in a standardized format using a common namespace. Currently, it provides access to hundreds of GSMs and pathways that can be interactively compared (two or more), analysed (e.g. detection of dead-end metabolites and reactions, flux balance analysis or simulation of reaction and gene knockouts), manipulated and exported. Users can also upload their own metabolic models, choose to automatically map them into the common namespace and subsequently make use of the website's functionality.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genomics
  • Humans
  • Internet
  • Metabolic Networks and Pathways* / genetics
  • Models, Biological
  • Software*