Changing concepts and findings on autism

J Autism Dev Disord. 2013 Aug;43(8):1749-57. doi: 10.1007/s10803-012-1713-7.


New research findings provide major challenges regarding our understanding of the concept of autism. These are critically discussed in relation to research relevant to classification, genetics, environmental risk factors, gene-environment interplay, animal models, biomarkers, clinical features, neuropathology, pharmacotherapy, behavioral treatments, and functioning in adult life. It is concluded that, although there have been major research advances; there is a need for a reconceptualization and an avoidance of claims that go beyond the evidence.

Publication types

  • Review

MeSH terms

  • Animals
  • Autistic Disorder* / classification
  • Autistic Disorder* / epidemiology
  • Autistic Disorder* / etiology
  • Autistic Disorder* / genetics
  • Disease Models, Animal
  • Humans