Design and measurements of low power multichannel chip for recording and stimulation of neural activity

M Zoladz; P Kmon; P Grybos; R Szczygiel; R Kleczek; P Otfinowski; J Rauza

doi:10.1109/EMBC.2012.6346959

Design and measurements of low power multichannel chip for recording and stimulation of neural activity

Annu Int Conf IEEE Eng Med Biol Soc. 2012:2012:4470-4. doi: 10.1109/EMBC.2012.6346959.

Authors

M Zoladz¹, P Kmon, P Grybos, R Szczygiel, R Kleczek, P Otfinowski, J Rauza

Affiliation

¹ AGH University of Science and Technology, Department of Measurements and Electronics, al. A. Mickiewicza 30, 30-059 Krakow, Poland. zoladz@agh.edu.pl

PMID: 23366920
DOI: 10.1109/EMBC.2012.6346959

Abstract

A 64-channel Neuro-Stimulation-Recording chip named NRS64 for neural activity measurements has been designed and tested. The NRS64 occupies 5×5 mm² of silicon area and consumes only 25 µW/channel. A low cut-off frequency can be tuned in the 60 mHz-100 Hz range while a high cut-off frequency can be set to 4.7 kHz or 12 kHz. A voltage gain can be set to 139 V/V or 1100 V/V. A measured input referenced noise is 3.7 µV rms in 100 Hz-12 kHz band and 7.6 µV rms in 3 Hz-12 kHz band. A digital correction is used in each channel to tune the low cut-off frequency and offset voltage. Each channel is equipped additionally with a stimulation circuit with an artifact cancellation circuit. The stimulation circuit can be set with 8-bit resolution in six different ranges from 500 nA-512 µA range.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Action Potentials / physiology*
Amplifiers, Electronic*
Analog-Digital Conversion*
Electric Power Supplies
Electric Stimulation / instrumentation*
Electroencephalography / instrumentation*
Equipment Design
Equipment Failure Analysis
Semiconductors
Signal Processing, Computer-Assisted / instrumentation*
Signal-To-Noise Ratio