Glutathione-functionalized graphene quantum dots as selective fluorescent probes for phosphate-containing metabolites

Jing-Jing Liu; Xiao-Long Zhang; Zhong-Xiao Cong; Zhi-Tao Chen; Huang-Hao Yang; Guo-Nan Chen

doi:10.1039/c3nr33794d

Glutathione-functionalized graphene quantum dots as selective fluorescent probes for phosphate-containing metabolites

Nanoscale. 2013 Mar 7;5(5):1810-5. doi: 10.1039/c3nr33794d. Epub 2013 Feb 1.

Authors

Jing-Jing Liu¹, Xiao-Long Zhang, Zhong-Xiao Cong, Zhi-Tao Chen, Huang-Hao Yang, Guo-Nan Chen

Affiliation

¹ The Key Lab of Analysis and Detection Technology for Food Safety of the MOE, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, PR China.

PMID: 23370282
DOI: 10.1039/c3nr33794d

Abstract

Bright blue fluorescent glutathione-functionalized graphene quantum dots (GQDs@GSH) were prepared by a one-step pyrolysis method with a fluorescence quantum yield as high as 33.6%. Futhermore, the obtained GQDs@GSH can be used as a probe to estimate the ATP level in cell lysates and human blood serum.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adenosine Triphosphate / blood*
Adenosine Triphosphate / metabolism
Cell Line, Tumor
Electron Transport
Fluorescent Dyes / chemistry*
Glutathione / chemistry
Glutathione / metabolism*
Graphite / chemistry*
Humans
Kinetics
Quantum Dots*
Quantum Theory
Spectrometry, Fluorescence*

Substances

Fluorescent Dyes
Graphite
Adenosine Triphosphate
Glutathione