[Chemical constituents of Acorus calamus]

Zhongguo Zhong Yao Za Zhi. 2012 Nov;37(22):3430-3.
[Article in Chinese]


Objective: To study the chemical constituents contained in Acorus calamus.

Method: The chemical constituents were separated and purified by various chromatographic methods including silica gel, ODS, HPLC and Sephadex LH-20, and their structures were identified on the basis of analysis on spectroscopic data.

Result: Ten compounds were separated from A. calamus and identified as 1beta, 4beta, 7alpha-trihydroxyeudesmane (1), bullatantriol (2), teuclatriol (3), threo-1', 2'-dihydroxyasarone (4), erythro-1', 2'-dihydroxyasarone (5), (+)-de-4'-O-methyleudesmin (6), (+)-de-4'-0-methylmagnolin (7), (+)-eudesmin (8), (+)-magnolin (9) and beta-sitosterol (10), respectively.

Conclusion: Compounds 1-2,4-9 were separated from this plant for the first time. Specifically, compounds 1-2,6-9 were obtained from Acorus genus for the first time.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acorus / chemistry*
  • Chromatography, High Pressure Liquid
  • Drugs, Chinese Herbal / chemistry*
  • Drugs, Chinese Herbal / isolation & purification
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Plant Roots / chemistry
  • Spectrometry, Mass, Electrospray Ionization


  • Drugs, Chinese Herbal