[The influence of intravenous laser therapy on prostaglandin E2 and F2-alpha dynamics and the state of microcirculation in the patients presenting with gastroesophageal reflux disease]

Vopr Kurortol Fizioter Lech Fiz Kult. Nov-Dec 2012;(6):17-20.
[Article in Russian]


The objective of the present work was to study the influence of low-frequency laser radiation on the levels of prostaglandins E2 and F2-alpha and characteristics of microcirculation in the patients suffering from gastroesophageal reflux disease (GERD). A total of 112 patients at the age from 19 to 79 years presenting with GERD were examined. 78 of them were given the complete 10-day course of intravenous laser therapy based on a Matriks-VLOK ("Matriks", Russia) therapeutic laser set emitting in the continuous mode at a wavelength of 0.405 mcm with the radiation power 1-11.5 mW at the output of the main lightguide. The characteristics of interest were determined before and after the treatment. It was shown that laser irradiation resulted in the elevation of pro-inflammatory prostaglandin levels and the improvement of parameters of microcirculation.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Dinoprost / blood*
  • Dinoprostone / blood*
  • Female
  • Gastroesophageal Reflux* / blood
  • Gastroesophageal Reflux* / physiopathology
  • Gastroesophageal Reflux* / radiotherapy
  • Humans
  • Low-Level Light Therapy* / instrumentation
  • Low-Level Light Therapy* / methods
  • Male
  • Microcirculation*
  • Middle Aged


  • Dinoprost
  • Dinoprostone