Intrauterine infusion of lidocaine does not reduce pain scores during IUD insertion

Contraception. 2013 Jul;88(1):37-40. doi: 10.1016/j.contraception.2012.12.009. Epub 2013 Jan 2.


Background: Potential pain with IUD insertion is a concern for women. Studies have found that systemic and local cervical therapies do not reduce pain scores. Since intrauterine infusion of lidocaine may reduce pain with endometrial aspiration, in this pilot study, we tested whether such infusion through an inexpensive endometrial aspirator could reduce IUD insertion pain scores with IUD insertion.

Study design: In this randomized, double-blinded, placebo control pilot study of 40 women undergoing IUD insertion, pain scores of women receiving 1.2 mL 2% lidocaine versus normal saline (1:1) infused 3 min prior to IUD insertion were measured using a 0-9-point scale.

Results: Pain at tenaculum placement was similar between groups. There was no difference in mean pain scores during IUD insertion of women infused with lidocaine (2.95) versus normal saline (3.75), p=.37. Considerable variation in pain scores was noted; 46% of subjects had pain scores ≤2 while 33% had pain scores ≥5.

Conclusion: Use of 2% lidocaine administered through an endometrial aspirator did not significantly reduce IUD insertion pain scores in this pilot study.

Trial registration: NCT01311102.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Administration, Intravaginal
  • Adult
  • Anesthetics, Local / administration & dosage*
  • Anesthetics, Local / therapeutic use
  • Double-Blind Method
  • Female
  • Humans
  • Infusions, Parenteral
  • Intrauterine Devices / adverse effects*
  • Intrauterine Devices, Copper / adverse effects
  • Intrauterine Devices, Medicated / adverse effects
  • Lidocaine / administration & dosage*
  • Lidocaine / therapeutic use
  • Outpatient Clinics, Hospital
  • Pain Measurement
  • Pilot Projects
  • Vacuum Curettage / instrumentation
  • Young Adult


  • Anesthetics, Local
  • Lidocaine

Associated data