Specialized and independent processing of orientation and shape in visual field maps LO1 and LO2

Nat Neurosci. 2013 Mar;16(3):267-9. doi: 10.1038/nn.3327. Epub 2013 Feb 3.

Abstract

We identified human visual field maps, LO1 and LO2, in object-selective lateral occipital cortex. Using transcranial magnetic stimulation (TMS), we assessed the functions of these maps in the perception of orientation and shape. TMS of LO1 disrupted orientation, but not shape, discrimination, whereas TMS of LO2 disrupted shape, but not orientation, discrimination. This double dissociation suggests that specialized and independent processing of different visual attributes occurs in LO1 and LO2.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Brain Mapping / methods
  • Female
  • Form Perception / physiology*
  • Humans
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neurons / physiology*
  • Orientation / physiology*
  • Photic Stimulation
  • Transcranial Magnetic Stimulation
  • Visual Cortex / physiology*
  • Visual Fields / physiology*
  • Visual Pathways / physiology