Multimodal pain management in orthopedics: implications for joint arthroplasty surgery

Orthopedics. 2013 Feb;36(2 Suppl):7-14. doi: 10.3928/01477447-20130122-51.


Multimodal pain management has become an important part of the perioperative care of patients undergoing total joint replacement. The principle of multimodal therapy is to use interventions that target several different steps of the pain pathway, allowing more effective pain control with fewer side effects. Many different protocols have shown clinical benefit. The goal of this review is to provide a concise overview of the principles and results of multimodal pain management regimens as a practical guide for the management of joint arthroplasty patients.

Publication types

  • Review

MeSH terms

  • Analgesics / administration & dosage*
  • Anesthesia, Spinal
  • Arthroplasty, Replacement*
  • Humans
  • Infusions, Intravenous
  • Nerve Block
  • Pain Management
  • Pain, Postoperative / drug therapy*


  • Analgesics