Personalised intervention for people with depression and severe COPD

Br J Psychiatry. 2013 Mar;202(3):235-6. doi: 10.1192/bjp.bp.112.120139. Epub 2013 Feb 7.

Abstract

Chronic obstructive pulmonary disease (COPD) is often complicated by depression and exemplifies the challenge in managing chronic illnesses that require active patient participation in care. In a clinical trial (NCT00151372), we compared a novel personalised intervention for depression and COPD (PID-C) targeting treatment adherence with treatment as usual (TAU). In 138 patients with major depression and severe COPD, PID-C led to a higher remission rate and a greater reduction in depressive symptoms and in dyspnoea-related disability than TAU over 28 weeks and 6 months after the last session. If replicated, PID-C may serve as a care model for patients with both depression and medical illnesses with a deteriorating course.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Depressive Disorder, Major / complications
  • Depressive Disorder, Major / drug therapy*
  • Depressive Disorder, Major / psychology
  • Disease Progression
  • Dyspnea / prevention & control
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Intention to Treat Analysis
  • Monte Carlo Method
  • Outcome Assessment, Health Care / statistics & numerical data*
  • Patient Compliance / psychology
  • Psychiatric Status Rating Scales
  • Pulmonary Disease, Chronic Obstructive / complications
  • Pulmonary Disease, Chronic Obstructive / physiopathology
  • Pulmonary Disease, Chronic Obstructive / rehabilitation*
  • Remission Induction
  • Survival Analysis