Personalised intervention for people with depression and severe COPD

Br J Psychiatry. 2013 Mar;202(3):235-6. doi: 10.1192/bjp.bp.112.120139. Epub 2013 Feb 7.


Chronic obstructive pulmonary disease (COPD) is often complicated by depression and exemplifies the challenge in managing chronic illnesses that require active patient participation in care. In a clinical trial (NCT00151372), we compared a novel personalised intervention for depression and COPD (PID-C) targeting treatment adherence with treatment as usual (TAU). In 138 patients with major depression and severe COPD, PID-C led to a higher remission rate and a greater reduction in depressive symptoms and in dyspnoea-related disability than TAU over 28 weeks and 6 months after the last session. If replicated, PID-C may serve as a care model for patients with both depression and medical illnesses with a deteriorating course.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Depressive Disorder, Major / complications
  • Depressive Disorder, Major / drug therapy*
  • Depressive Disorder, Major / psychology
  • Disease Progression
  • Dyspnea / prevention & control
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Intention to Treat Analysis
  • Monte Carlo Method
  • Outcome Assessment, Health Care / statistics & numerical data*
  • Patient Compliance / psychology
  • Psychiatric Status Rating Scales
  • Pulmonary Disease, Chronic Obstructive / complications
  • Pulmonary Disease, Chronic Obstructive / physiopathology
  • Pulmonary Disease, Chronic Obstructive / rehabilitation*
  • Remission Induction
  • Survival Analysis