Additional effects of taurine on the benefits of BCAA intake for the delayed-onset muscle soreness and muscle damage induced by high-intensity eccentric exercise

Adv Exp Med Biol. 2013;776:179-87. doi: 10.1007/978-1-4614-6093-0_18.

Abstract

Taurine (TAU) has a lot of the biological, physiological, and pharmocological functions including anti-inflammatory and anti-oxidative stress. Although previous studies have appreciated the effectiveness of branched-chain amino acids (BCAA) on the delayed-onset muscle soreness (DOMS), consistent finding has not still convinced. The aim of this study was to examine the additional effect of TAU with BCAA on the DOMS and muscle damages after eccentric exercise. Thirty-six untrained male volunteers were equally divided into four groups, and ingested a combination with 2.0 g TAU (or placebo) and 3.2 g BCAA (or placebo), thrice a day, 2 weeks prior to and 4 days after elbow flexion eccentric exercise. Following the period after eccentric exercise, the physiological and blood biochemical markers for DOMS and muscle damage showed improvement in the combination of TAU and BCAA supplementation rather than in the single or placebo supplementations. In conclusion, additional supplement of TAU with BCAA would be a useful way to attenuate DOMS and muscle damages induced by high-intensity exercise.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acids, Branched-Chain / administration & dosage
  • Amino Acids, Branched-Chain / pharmacology
  • Amino Acids, Branched-Chain / therapeutic use*
  • Area Under Curve
  • Biomarkers / blood
  • Exercise*
  • Feeding Behavior* / drug effects
  • Humans
  • L-Lactate Dehydrogenase / blood
  • Male
  • Muscle Weakness / blood
  • Muscle Weakness / drug therapy*
  • Muscle Weakness / enzymology
  • Muscle, Skeletal / drug effects
  • Muscle, Skeletal / pathology*
  • Pain Measurement
  • Taurine / administration & dosage
  • Taurine / pharmacology
  • Taurine / therapeutic use*
  • Young Adult

Substances

  • Amino Acids, Branched-Chain
  • Biomarkers
  • Taurine
  • L-Lactate Dehydrogenase