TP53 mutations are frequent in adult acute lymphoblastic leukemia cases negative for recurrent fusion genes and correlate with poor response to induction therapy

Haematologica. 2013 May;98(5):e59-61. doi: 10.3324/haematol.2012.076786. Epub 2013 Feb 12.
No abstract available

Keywords: TP53 mutations; adult acute lymphoblastic leukemia; response to induction chemotherapy.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Humans
  • Mutation*
  • Oncogene Proteins, Fusion
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Remission Induction
  • Treatment Outcome
  • Tumor Suppressor Protein p53 / genetics*


  • Oncogene Proteins, Fusion
  • TP53 protein, human
  • Tumor Suppressor Protein p53