Copper-catalysed oxidative C-H/N-H cross-coupling between formamides and amides through chelation-assisted N-H activation

Org Biomol Chem. 2013 Mar 28;11(12):1925-8. doi: 10.1039/c3ob40094h. Epub 2013 Feb 14.

Abstract

A copper-catalysed oxidative C-H/N-H cross-coupling between formamides and amides through chelation-assisted N-H activation has been developed for the preparation of various multi-substituted ureas.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amides / chemistry*
  • Catalysis
  • Chelating Agents / chemistry*
  • Copper / chemistry*
  • Formamides / chemistry*
  • Molecular Structure
  • Oxidation-Reduction
  • Urea / analogs & derivatives
  • Urea / chemical synthesis*
  • Urea / chemistry

Substances

  • Amides
  • Chelating Agents
  • Formamides
  • Copper
  • Urea