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Case Reports
, 60 (7), E38-41

Successful Treatment of Pediatric Plasmacytoid Dendritic Cell Tumors With a Contemporary Regimen for Acute Lymphoblastic Leukemia

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Case Reports

Successful Treatment of Pediatric Plasmacytoid Dendritic Cell Tumors With a Contemporary Regimen for Acute Lymphoblastic Leukemia

Karen D Wright et al. Pediatr Blood Cancer.

Abstract

Dendritic cell leukemia (DCL) or hematodermic tumor is an uncommon subtype of acute leukemia. In contrast to adult cases, children tend to have a less aggressive course. The diagnosis of DCL should be considered when its characteristic morphologic features are present and leukemic cells co-express CD4 and CD56. Cases of DCL among pediatric patients have been reported to respond to therapeutic regimens for acute lymphoblastic leukemia, but details regarding the specifics of therapy are lacking.

Conflict of interest statement

Disclosures

The authors have no disclosures or competing financial interests.

Figures

Fig. 1
Fig. 1
A. Morphology of peripheral blood and B. cerebrospinal fluid shows blasts with scant, pale, basophilic, vacuolated cytoplasm. Bone marrow morphology reveals C. prominent cytoplasmic projections and D. peripheral vacuolization resembling a string of pearls.

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