Whole animal experiments should be more like human randomized controlled trials

PLoS Biol. 2013;11(2):e1001481. doi: 10.1371/journal.pbio.1001481. Epub 2013 Feb 12.


The quality of reporting of animal studies lags behind that of human randomized controlled trials but a series of additions to the ARRIVE guidelines will help ensure that the standards are comparable.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animal Experimentation / standards*
  • Animals
  • Randomized Controlled Trials as Topic
  • Research Design

Grant support

BSM is supported by a Career Development Fellowship from the National Health and Medical Research Council of Australia. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.