Mutation rates: how low can you go?

Curr Biol. 2013 Feb 18;23(4):R147-9. doi: 10.1016/j.cub.2013.01.018.


Two recent reports combine mutation accumulation and whole-genome sequencing to measure mutation rates in microbes with unusual genome sizes and life cycles. The results are broadly consistent with the hypothesis that genetic drift plays a role in shaping genomic mutation rates across a wide range of taxa.

MeSH terms

  • Chlamydomonas reinhardtii / genetics
  • Entomoplasmataceae / genetics
  • Evolution, Molecular
  • Genetic Drift*
  • Genetic Variation
  • Genome
  • Genome Size / genetics*
  • Mutation Rate*
  • Paramecium tetraurelia / genetics